be solved with the same quality thanks to the level achieved by the Cuban National Health System as well as the proved efficacy of Recombinant Epidermal Growth Factor (EFG) (Heberprot-P) and the training of the personnel who work in the welfare health areas.

Objective: To Evaluate the diabetic foot treatment using Heberprot-P in the primary health assistance in Cuba.

Patients & method: Our universe was composed by 1551patients assisted consecutively in four welfare health areas. All of them received 15 to 24 intralesional injections of 75micrograms each, three times a week. They were under went to surgical operations when required under nerve trunk anesthesia on the leg. An informed consent was signed previously. The variables analyzed were: Age, sex, Wagner classification, doses administered, surgical procedures and final result.

Results: In our series 407 debridement were carried out (26%), 77 toe amputations (4, 96 %) and 3 metatarsal amputations (0, 19%). No major amputations were carried out. A satisfactory granulation was achieved in all patients. The adverse reactions were 17 (1, 1%) all of them were mild. Nobody quit the treatment and there were no mortality.

Conclusions: Among our patients the treatment were 100% effective the rate of amputations were low. The adverse events were few and mild.be solved with the same quality thanks to the level achieved by the Cuban National Health System as well as the proved efficacy of Recombinant Epidermal Growth Factor (EFG) (Heberprot-P) and the training of the personnel who work in the welfare health areas.

Objective: To Evaluate the diabetic foot treatment using Heberprot-P in the primary health assistance in Cuba.

Patients & method: Our universe was composed by 1551patients assisted consecutively in four welfare health areas. All of them received 15 to 24 intralesional injections of 75micrograms each, three times a week. They were under went to surgical operations when required under nerve trunk anesthesia on the leg. An informed consent was signed previously. The variables analyzed were: Age, sex, Wagner classification, doses administered, surgical procedures and final result.

Results: In our series 407 debridement were carried out (26%), 77 toe amputations (4, 96 %) and 3 metatarsal amputations (0, 19%). No major amputations were carried out. A satisfactory granulation was achieved in all patients. The adverse reactions were 17 (1, 1%) all of them were mild. Nobody quit the treatment and there were no mortality.

Conclusions: Among our patients the treatment were 100% effective the rate of amputations were low. The adverse events were few and mild.