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Erythema multiforme: a case series and review of literature


Open Access Journal of Translational Medicine & Research
Keerthi Krishnankutty, Kanad Chaudhuri, Lingappa Ashok
Bapuji Dental College and Hospital
Keerthi Krishnankutty, Department of Oral Medicine and Radiology, Bapuji Dental College and Hospital, India
Lingappa Ashok, Department of Oral Medicine and Radiology, Bapuji Dental College and Hospital, India

Abstract

Erythema Multiforme (EM) is an acute, immune-mediated condition, most commonly induced by Herpes Simplex Virus (HSV) infection, or by the use of certain medication and presents with cutaneous or mucosal lesions or both. Characteristic lesions are seen over the skin as distinctive target-like lesions with concentric color variation, sometimes accompanied by oral, genital, or ocular mucosal erosions or bullae. EM is usually self-limiting; however, frequent episodes over the years can lead to recurrent disease in a small group of patients. Patients can present with oral and lip lesions typical of EM without any evidence of skin lesions. It has also been reported that primary EM can be confined to the oral mucosa but the subsequent attacks can produce more severe forms of cutaneous EM. We present 3 case scenarios of EM minor managed in our department along with a review of the pathogenesis, clinical features, and management of EM.

Keywords

erythema multiforme, herpes simplex virus, stevens johnson syndrome, burning sensation, buccal mucous, hyper salivation, halitosis, diagnosis, ,erythema multiforme,toxic epidermal

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