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Intrinsic subtypes of breast cancer in malignant speculating mass on mammography

International Journal of Radiology & Radiation Therapy
Andreas Aryo Bayu Seto,1 Lies Mardiyana2


Background:Speculated mass is one of the indications for malignancy in mammography. Breast cancer can be divides into four intrinsic subtypes, Luminal A, Luminal B, HER2+ and basal-like/triple negative. Each with differing prognosis, Luminal A and B has a better prognosis than HER2+ and the worst prognosis being the basal-like subtype.
Objective:To describe each intrinsic breast cancer subtypes that have the appearance of malignant speculated mass in mammography.
Material and method:This was a retrospective cross sectional study that used medical record data using consecutive sampling between January 2017 and December 2018 in Dr. Soetomo Surabaya General Hospital. The mammography images of speculated mass were reviewed by a breast imaging consultant of radiology. The pathological results were obtained from the medical record data.
Result: We found that breast cancer with a mammographic appearance of speculated mass, the majority of them were of Luminal A subtype, followed with Luminal B, HER2+ and Basal-like subtypes
Conclusion:In this study, we found the majority of breast cancer with a mammographic appearance of speculated mass was of the subtype Luminal A.


malignant mass, mammography, intrinsic subtypes, luminal A, luminal B, HER2+, Basal-like/triple negative