Home Magazines Editors-in-Chief FAQs Contact Us

Evaluation of risk factors for cardiovascular disease on rheumatoid arthritis patients from outpatient clinic


MOJ Gerontology & Geriatrics
Vitor Moraes Rocha

PDF Full Text

Abstract

Background: Rheumatoid arthritis (RA) is associated with increased cardiovascular mortality 10 yearsearlier compared with the general population. Endothelial dysfunction in coronary and cerebrovascular arteries are considered the cause of this premature higher risk.This study focuses on evaluating the risk of developing CVD in a 10 years perspective in patients with RA.Methods: Retrospective data analysis of 78 patients with diagnosis of RA was performed. The risk score of Acute Coronary Disease in 10 years was calculated in accordance to the Framingham Heart Study; Control group (CG) with 21 patients - osteoarthritis and fibromyalgia was also assessed using the same criteria. Age, sex, SBP??, total cholesterol, cholesterol HDL, smoking status and diagnosis of diabetes were scored.

Results: RA patients had a mean disease duration of 12.8 years (SD=7.4), aged 58.6 years (SD=10.3); CG 59.3 years (SD=10,0). Total cholesterol, HDL, Higher SBP and being diagnosed with Diabetes Mellitus showed positive correlations with the higher Cardiovascular Disease (CVD). Global CR in each group were considered low (7,8 points to RA and 9,3 CG).

Conclusion: The RA group did not show a greater risk of CVD when compared to CG. We highlight the fact that the CG higher prevalence of diabetics and under reporting of DM in RA medical records probably impacted the results. Preventive measures should be introduced even in patients with low CVR, and in special for those with chronic inflammatory diseases such as RA.

Keywords

rheumatoid arthritis, cardiovascular diseases, criteria framingham, fibromyalgia, osteoarthritis, rheumatological diseases, inflammatory process, ischemic heart disease, clinical practice, secondary prevention, hypercholesterolemia, blood pressure, body mass index, diabetes diagnosis

Testimonials