Abstract

Sickle cell disease is an inherited monogenic disease characterized by misshapen red blood cells that causes vaso- occlusive disease, vasculopathy, and systemic inflammation. We report a case of a 24 years old black female with sickle cell disease (SCD), (hemoglobin S 30%), at her twelfth week of pregnancy, with fever, myalgia, productive cough and leucorrhea. Chest radiography demonstrated bilateral infiltrates and a microcytic anemia of 7.4g/dL. The patient was hospitalized with the diagnostic of acute chest syndrome and treatment  with  ceftriaxone  1g/day,  hydration  and  analgesic  therapeutic  to  pain  relief. However, because of resistant abdominal pain to paracetamol and tramadol and laboratory studies with hemoglobin value of 7g/dL, a compatible blood transfusion was done. Despite the better recognition and diagnosis, pregnancy in SCD is associated with higher clinical and obstetric complications compared to healthy individuals. So, this case demonstrates the importance of an access to multidisciplinary care team to decrease significantly themorbidity and mortality of these cases.

Keywords

pregnancy, sickle cell disease,anemia in pregnancy, blood transfusion,abdominal pain