Abstract

Dengue is the most common endemic disease in tropical region transmitted to humans by mosquitoes of Aedes species and often manifests to be fatal. In recent decades the prevalence and circulation of dengue has upturned dramatically. Unplanned development of cities without proper water management system is the main reason for spread of dengue. The true burden of dengue is unclear due to reported data. Dengue showing a wide range of symptoms is easily misdiagnosed and it does not have a specific treatment. With the increase in the number of dengue affected population there is an urge to develop effective and specific treatment for dengue. For unfolding this problem development of potential vaccine against dengue which is also cost effective would be an ideal fix. In this review we focus on using genetic engineering tools in turning plants as the biofactories for developing efficient vaccines against Dengue.

Keywords

dengue virus, aedes aegypti, vaccine development, plant molecular farming