Abstract

Pemphigus vulgaris (PV) is a bullous disease. It has autoimmune etiology. It mainly affects skin along with mucous membranes. The frequency and pattern of involvement of eyes in this disease is not clearly defined till now. We decided to conduct a study of hundred patients with diagnosis of PV in a tertiary care hospital in Pakistan. The result showed a significant number of patients with eye involvement, 32 out of 100 cases in the indoor department of hospital i.e. (32%) showed eye involvement in a variable range of severity and presentation. Most common symptom was conjunctivitis followed by palpebral conjunctival erosions. Discharge was present in few patients that was either watery or mucoid due to the secondary infection.

Keywords

pemphigus vulgaris, bullous disease, conjunctivitis, immunosuppressive medicines, epithelial cell junction, ocular involvement, cyclophosphamide, mycophenolate, mofetil