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Anxiolytic effect of olive leaf tea on mice


Journal of Analytical & Pharmaceutical Research
Sana sarfaraz,1 Tanveer bano,2 Hafsa khalid,2 Aimen zafar,2 Anoosha atique,2 Areesha rashid2

Abstract

According to current scenarios, the daily lifestyle of majority of the population is full of stress, worry and anxiety. This life style is also imparting its great role in psychological disorders. To improve the mental conditions, along with keeping a healthy life style, it is better to incorporate natural ingredients in diet. Historically, olive leaves have been used for medicinal purposes as well as being considered a symbol of peace. A study was conducted to evaluate the anxiolytic effect of olive leaf tea on mice. Distilled water 0.2mL was used as control and administered to 6 mice labeled as Group I whereas Olive leaf tea was prepared freshly with dried olive leaves and administered orally at 0.2mL to 6 mice labeled as Group II (treated) for 28 days. To evaluate CNS activity, a number of tests were performed including: Head dip, Cage crossing and Open field test. Upon evaluation of results, marked decrement was seen in number of head dips, cage crossing and also in central and peripheral square crossing. In accordance with the above result, it was concluded that the phenolic compound in olive leaves i.e. Oleuropein possesses some anxiolytic activity, besides its other known various pharmacological activities. Not only can olive leaf tea be prepared freshly at home, it has no known side effects and is economical. Therefore it can bestow a great part in preventing psychological disorder as well as imparting healthy life style.

Keywords

anxiety, cage crossing, head dip, open field, oleuropein, olive leaf, trauma, allopathic drugs, neurotransmitters, antimicrobial, antiviral, skin protectant, anti-aging, neuro-protective, anti-diabetic

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