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A cross sectional descriptive study on hydatidiform mole at Gambian tertiary hospital


MOJ Women's Health
Matthew Anyanwu,1,2,3 Kajaly Bah1

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Abstract

Background/Aims: Hydatidiform mole is the non- malignant form of gestational trophoblastic neoplasia. The prevalence of 1:250 to 1:500 has been reported which vary widely in different parts of the world. Therefore, Knowledge of prevalence and associated risk factors may add value in the management outcomes of molar pregnancy in our setting.
Methods: A cross-sectional study of hydatidiform mole at the gynecology clinic of Edward Francis Small Teaching Hospital (EFSTH) from January 2016 to January 2018. Data was collected from patients’ folders, entered into SPSS and analyzed with descriptive statistics. Association between variables was done using Non-parametric test (Kolmogorov-smirnov test) on SPSS.
Result: The prevalence of molar pregnancy was 9.46 per 1000 women. The most affected age group was 26-40 years (60%) whereas only 10% of molar pregnancy occurred in those above 40 years. Multiparity (55%) and blood group B+ (35%) recorded higher percentage. Test of significance showed strong association with occupation (p-value 0.000) of which 90% of women were house wives. There was no correlation between parity (Pearson correlation is -0.33; the p value 0.89); and maternal age (Pearson correlation 0.248; p value 0.291) at presentation with progression to invasive GTN.
Conclusion: The study suggests a high prevalence rate. Multigravidas, age group (26-40 years), B positive and house wives were associated with molar pregnancy.
 

Keywords

hydatidiform, mole, prevalence, risk, factors, partial moles, evacuation, socio-demographic characteristics

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