Purpose: The purpose of this study was to compare the efficacy of treatment modalities of diabetic macular edema.

 

Methods: This interventional study was done from August 2018 to May 2019 at Madinah Teaching Hospital, Faisalabad. 30 subjects were selected by Convenient Sampling technique, aged between 30-70 years, male and female gender was included. Study design was interventional. Eyes were randomized to grid laser photocoagulation (N=15) and Anti-VEGF (N=15). Consent was taken from the selected participants with diabetic macular edema. Visual acuity and retinal thickness were recorded before and after the treatment therapies. Data analysis was done by latest SPSS version.

 

Results: A total of 30 patients were included in our interventional study. Intravitreal Avastin improved BCVA most significantly (OR: +7.01 95%CI (2.56 to 11.39)) in 1 month followup and Laser less significantly (+8.19 (5.07 to 11.96)) in one month follow up. Intravitreal Avastin decreased retinal thickness most significantly (-111.34 (-254.61 to 37.93)) in one months and Laser decreased less significantly.SPSS showed that significant result less than 0.005.

 

Conclusion: Avastin therapy was found more effective in diabetic macular edema management than the Laser therapy in follow-ups.