Total synthesis of the civet constituent (-)-2-((2R, 6R)-6-methyltetrahydro-2H-pyran-2-yl) acetic acid
- MOJ Bioorganic & Organic Chemistry
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Fátima Garrido,1,2 Hugo Santalla,1,2 Generosa Gómez,1,2 Yagamare Fall1,2
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Abstract
We describe the total synthesis of a glandular secretion of the Civet Cat, using tri-O-acetyl-D-glucan, a cheap and commercially available chiral building block.
Keywords
Tetrahydropyran, Civet cat compound, Natural product, Glandular secretion, Chiral reagent, MOM protection, Wolf-Kushner reaction, Alcohol
