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Non-specific immunostimulatory effects of transfer factor

International Clinical Pathology Journal
Vaclav Vetvicka, Fernandez-Botran R

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The focus of this study was to confirm the hypothesis that food supplementation with colostrum- and egg-derived transfer factor can positively influence immune reaction. Our results found that phagocytosis, proliferation of spleen cells, NK cell cytotoxicity, IL-2 and IFN-γ production were significantly stimulated by feeding with transfer factor. Production of antibodies and IL-4, IL-5, IL-10 and TNF-α and the cellular composition of spleen was not affected. From our data we conclude that this type of transfer factor affects both cellular and humoral branch of immune reactions.


NK cell cytotoxicity, spleen cells, IL-2 and IFN-?