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Rare association of eosinophilic pancreatitis and ulcerative colitis: a case report and a review of the literature

Gastroenterology & Hepatology: Open Access
Samlani Z,1 Lemfadli Y,1 Habiyaremye C,1 Ait Errami A,1 Oubaha S,2 Rais H,3 Krati K1

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infiltration of the pancreatic gland by eosinophilic polymorphonuclear cells. It poses the problem of differential diagnosis with a pancreatic tumor, hence the interest of histological evidence by invasive means.

Case report:We present a case of eosinophilic pancreatitis in a 37-year-old man who was diagnosed after an endoscopic biopsy in front of an obstructive mass of the head of the pancreas simulating a pancreatic tumor. In contrast to the data in the literature, our patient had only eosinophilic infiltration of the pancreas with no history of symptoms related to hyper-eosinophilia or to a high level of immunoglobulins E. The second peculiarity in our patient is the concomitant revelation of ulcerative colitis.

Conclusion:Eosinophilic pancreatitis is a rare and often misdiagnosed clinical situation. Correct and precise diagnosis avoids unnecessary interventions. Echo-endoscopy with sample for histological study presents a fundamental means for the diagnosis of eosinophilic pancreatitis.


eosinophilic pancreatitis, eosinophils, ulcerative colitis, echo-endoscopy, PE, Eosinophilic pancreatitis, MRI, magnetic resonance cholangiography, CP, chronic pancreatitis