Abstract

Vogt-Koyanagi-Harada    syndrome    is    a    chronic    bilateral    autoimmune    intraocular    inflammation  in  which  antibodies  are  produced  against  melanocyte  tissues  associated with  neurological  and  skin  changes,  including  headache,  tinnitus,  vitiligo,  polyiosis,  and  alopecia.  The  disease  occurs  in  distinct  phases:  the  prodromal  phase,  the  acute  uveitic  phase, the chronic or convalescent phase, and the chronic recurrent phase. The treatment should be early and is made using corticosteroids and immunomodulatory drugs. We report a case of a young patient with the syndrome who developed recurrence of the disease during oral corticosteroid weaning, and was treated with adalimumab.

Keywords

vogt-koyanagi-harada syndrome, panuveitis, exudative retinal detachment