Successful management of severe lupus crescentic nephritis and pneumonitis with weekly cyclophosphamide and plasmapheresis
- Urology & Nephrology Open Access Journal
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Ahmed Akl,1,7 Nahid Janodi,2 Souha Issa,3 Nabih Hammad,4 Wail Tashkandi,4 Sayed Asghar,5 Hassan A Shabana,5,8 Nezar Bahabri,6 Hanadi Alhozali,1 Mohamed Azzam4
Abstract
Systemic lupus erythematosus (SLE) may present with a variety of pulmonary manifestations. The most common is infection however lupus pneumonitis can be presented with a picture like infectious pneumonia. Lupus pneumonitis is a high suspicious in a postpartum young female presenting with pulmonary infiltrates. Type II rapidly progressive glomerulonephritis (RPGN) caused by immune complexes deposition accounts for 25% of RPGN. In-here, we present a catastrophic lupus pneumonitis and RPGN who responded well to intensive protocol of weekly cyclophosphamide and plasmapheresis.
Keywords
lupus pneumonitis, lupus erythematosus, cyclophosphamide, plasmapheresis, pulmonary infiltrates, antibodies
