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Impact of anemia in patient with asthma


Hematology & Transfusion International Journal
Waseem F Al-Tameemi,1 Rafid Th Habeeb2

Abstract

Background: Asthma varied in severity of exacerbations based on symptoms and pulmonary function. Anemia and functional iron status can significantly modulate its presentation. Objectives: This study aimed to define the clinical impact of anemia in asthma patient and to assess its correlation with severity of presentation. Patients and method: This is a cross sectional study conducted from the 1st of February 2017 until the 1st of December 2018 in the medical ward and the outpatient respiratory clinic at different general hospitals. Fifty patients with bronchial asthma were included. Every eligible patient was sent for complete blood count (CBC) and iron profile for anemic patient, in addition to assessment of pulmonary function test (PFT) and peak expiratory flow rate (PEF) with oxygen saturation. Results: The mean age of patients was 44 years with female predominance .Twenty five patients were anemic. Iron deficiency anemia proved in 16 of them. The mean level of hemoglobin was 13.37±2.07 g/dl. Forced expiratory volume in 1st second (FEV1), oxygen saturation and PEF were lower in patients with acute exacerbation than chronic stable group, the mean value was (47.01±21.93 L), (93.06 ±3.15%) and (147.68±79 L) respectively. PEF rate showed significant statistical difference between asthmatic anemic patients and those who were non anemic (P = 0.026). Serum Iron was significantly lower in acute than chronic presentation (P= 0.019). There was no relationship between the state of anemia and severity of asthma. Conclusion: The presence of anemia and lower iron status may associate with lower peak expiratory flow rate especially in acute asthma presentation.

Keywords

anemia, iron deficiency, asthma, pulmonary function, oxygen saturation

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