Long-term complete remission under TDM1 and local radiotherapy treatment on an inflammatory HER2-positive breast cancer
- Obstetrics & Gynecology International Journal
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Miguel Borregón, Katherin Martínez, Irene Ramos, Alba Ramos, Manuel Alejandro Mazariegos, Beatriz Berzal, Cristina Gómez, Margarita Díez, Irene Otero, Juan David Cárdenas, José Ignacio Chacón, Carmen Esteban
Abstract
Premenopausal female patient is diagnosed at the age of 45 with locally advanced inflammatory HER2-positive breast cancer with axillary node involvement. Her disease reveals bad prognostic factors. In spite of radical mastectomy after intensive neoadjuvant treatment based on chemotherapy and trastuzumab-pertuzumab, early skin infiltration recurrence overcomes. She receives local radiotherapy and TDM1 therapy as first advanced disease line. Toxic side effects are not relevant. She achieves four-years-long disease-free survival. Precise treatment selection is challenging but can find out cancer defeat.
Keywords
Premenopausal patient, Breast cancer, Inflammatory, Homolateral axillary