Determination of nephrotoxic effects due to Sugammadex and Rocuronium administration in rats
- Journal of Anesthesia & Critical Care: Open Access
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Oznur Uludag, Zumrut Dogan, Ebru Annaç
Abstract
Nowadays, neuromuscular blocker rocuronium and antagonizing sugammadex are being used in anesthesia practice. Rocuronium and sugammadex complexes are eliminated via the kidneys. The aim of this study was to investigate the effects of sugammadex and rocuronium plus sugammadex on histopathological evaluation and antioxidant status of kidney tissue for nephrotoxic effect.
Keywords
Kidney, Neuromuscular block, Rat, Rocuronium, Sugammadex