Abstract

LGI-1 is mainly expressed in the limbic areas involving temporal cortices and hippocampus. Anti -LGI-1 encephalitis is an autoimmune encephalitis which manifests with cognitive impairment, seizures which are mostly faciobrachial dystonic type and recurrent hyponatremia. We present an 82 year old octogenarian with similar such presentation with recurrent episodes of hyponatremia and cognitive decline having an excellent response to immunotherapy. There has been no mention of a similar presentation in this age group in literature, to the best of our knowledge.

Keywords

Anti LGI-1 encephalitis, refractory status epilepticus, elderly, hyponatremia