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Functional performance of children with Myelomeningocele submitted to intrauterine repair and conventional surgery


Journal of Neurology & Stroke
Maria Beatriz Silva e Borges,1 Paula Cristina Pereira,2 Kelly Letícia Boscato,3 Marisete Peralta Safons,4 Vitor Gabriel Carioca5

Abstract

Myelomeningocele (MMC) is an embryonic malformation that occurs in the first four weeks of gestation due to a failure in the closure of the neural tube. They have multifactorial etiology such as genetic and environmental factors that affect folic acid metabolism. Several anomalies may be associated with MMC, with the occurrence of hydrocephalus and Arnold Chiari type II malformation being most present. Surgical repair should ideally occur within the first 24 hours after birth to prevent or decrease the risk of infection, preservation of all viable nerve tissue, anatomical reconstitution. However, surgical repair of MMC intrauterine has shown substantial benefit in all babies submitted to this intervention.

Keywords

myelomeningocele, children, intrauterine repair, traditional surgery, PEDI

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