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Genetic polymorphism of eleven STR loci in Rajput population of Delhi, India


Forensic Research & Criminology International Journal
Tanya Chauhan, Kushwaha KPS, Varsha Chauhan
LNJN National Institute of Criminology and Forensic Science, India
KPS Kushwaha, LNJN National Institute of Criminology and Forensic Science, India
Varsha Chauhan , LNJN National Institute of Criminology and Forensic Science, India

Abstract

This study is an attempt to generate genetic database for endogamous population of Rajputs of Delhi, India. Genetic polymorphism at eleven Short Tandem Repeat (STR) loci (F13A01, FESFPS, vWA, D16S539, D7S820, D13S317, HPRTB, F13B, CSF1PO, TH01 and TPOX) was examined in 87 unrelated Rajputs individuals to evaluate their significance in human identification. There was no evidence for departures from HWE (P>0.001) at all loci except locus HPRTB. All the loci showed high polymorphism with great power of exclusion. The combined matching probability (MP) of the eleven STR system was 1.965 x 10-11, indicating that the system has a much stronger inter-individual discriminating power. The eleven loci showed a combined power of discrimination (PD) of 0.999999. The data suggests that these loci are useful for identity testing, forensics and for solving paternity cases among the Rajput population in Delhi, India.

Keywords

DNA, STR Loci, Genetic Diversity, Population Data, Rajputs, Forensics, Linguistic, Colonial Period, Geno Sequencer, Acrylamide Gel, Genotype, Heterozygosity, Paternity Tests, Heterozygosity, Discrimination, Forensic Databases, Indigenous Population

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