The worldwide metabolic syndrome prevalence in people living with HIV: a systematic review
- MOJ Food Processing & Technology
-
Sandro Rodrigo Barbosa da Silva,1
Beatriz
Marques Ramos,2
Elisama Gomes de
Santana,2
Adrielle Silva de Oliveira,3
Luciana
Costa Melo4
Abstract
Metabolic alterations have been reported in people living with HIV (PLHIV), related
to viral infection, side effects of antiretroviral therapy, genetic, environmental and/or
sociodemographic factors. We aimed to draw a global picture of prevalence of Metabolic
Syndrome (MetS) in PLHIV. We performed a systematic review based on the PRISMA
Statement method. We selected studies that investigated epidemiological characteristics
of PLHIV who developed MetS in 4 databases: PubMed, SciELO, LILACS and
Science Direct, using descriptors: HIV; prevalence; metabolic syndrome; epidemiology;
antiretroviral therapy, highly active. A total of 1117 articles were identified, including 98
in the final analysis. The prevalence of MetS ranged from 7.8 to 55.8% (Internacional
Diabetes Federation - IDF) and 7.1 to 58% (National Cholesterol Education Program Adult
Treatment Panel III - NCEP/ATP III), being higher in African women than in African men
(IDF), whereas European women and women of unknown origin were lower than women
from Asia, South and North America (NCEP/ATP III). There is a high prevalence of MetS
in PLHIV. The importance of multidisciplinary follow-up and encouragement of lifestyle
changes in PLHIV is emphasized.
Keywords
HIV, metabolic syndrome, prevalence, epidemiology, AIDS, systematic review, multidisciplinary
