Abstract

Recently, we have presented the first 3D images of the sea star Antibody (anti-HRP) - HRP Antigen complex in Alpha Fold 3, with minor details. In the present study, we used 4 systems of 3D representation, which are all issued from Alpha Fold, to illustrate this same complex. It appears clearly that these models, by using the ITPM parameter give contradictory results. Nevertheless, we start from the principle that in Science, we must be transparent. Nevertheless, it’s the first time, we present such models concerning an invertebrate primitive antibody: you understand that comparisons with other antibody 3D models seem difficult to establish, in the present time.

Keywords

sea star antibody, anti-HRP antibody, HRP antigen, alphafold 3, antigen– antibody complex, 3D molecular modeling, invertebrate immunity, protein–protein interactions