Su-al-Qinniya (Anemia) is a condition where there is a decrease in blood volume and alterations in its components, accompanied by a reduction in the number of Kurriyat-e-Hamrah (Red Blood Cells). This condition can arise from various factors, including inadequate dietary intake, low socioeconomic status, persistent illnesses, poor iron absorption, ongoing blood loss, and conditions such as bleeding peptic ulcers, inflammatory bowel disease, hookworm infestation, hemorrhoids, and heavy menstrual bleeding. Specific health situations like pregnancy and rapid growth can also trigger Iron Deficiency Anemia (IDA). In Unani literature, anemia has been described by various names such as Faqr al dam, Sū’-al-Qinniya, Qillatuddam, Kamie khoon, and Fasad’ al dam. The abnormal cold temperament of the liver is attributed to dryness and decreased blood, leading to paleness of the body. Anemia may also develop when the liver becomes functionally weak, causing alterations in temperament. This review paper outlines the etiopathogenesis, clinical presentation, various regimens, and herbal formulations used in the management of Su-al-Qinniya (Anemia).