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Von willebrand disease and gastrointestinal bleeding: case presentation

Hematology & Transfusion International Journal
Ariel Raúl Aragón Abrantes,1 Danelis Hernández Aguiar,2 Nidia Crespo Toledo,3 Carmen Ulloa Olivera3


Introduction: Von Willebrand diseases is a hereditary bleeding disorder caused by a quantitative or qualitative deficiency of von Willebrand factor, characterized by light mucocutaneous bleeding, although other bleeding such as gastrointestinal and joint bleeding may occur in severely affected patients. It treatment is fundamentally based on replacement therapy and the use of desmoprecin. Objective: Describe the characteristics and clinical evolution of a patient who presented upper gastrointestinal bleeding as a form of presentation of von Willebrand disease. Conclusions: von Willebrand diseases hould be suspected in patients with abnormal bleeding symptoms without apparent causes.


von Willebrand disease, digestive bleeding