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Platelets transfusion in dengue patients

Hematology & Transfusion International Journal
Aysha Khan,<sup>1 </sup> Shagulla Y,<sup>1</sup> Abeera A,<sup>1 </sup> Rehan AN,<sup>1</sup> Rizwan S,<sup>1</sup> Saad M<sup>2</sup>

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Objective: To investigate the role of platelet transfusion in dengue patients. Study design: Cross sectional prospective. Place and duration: Study was carried out at Combined Military Hospital Malir Cantonment Karachi from Oct 2019 to July 2022 Materials and methods: All the patients who were confirmed cases of Dengue by serology tests either by NS1 antigen, IgM or both were included in the study. Clinical features were analyzed and need for blood product was assessed, specifically platelet transfusion. Results: Out of 2000 dengue patients, 202 (10.1%) presented with some sort of haemorrhagic manifestations. 82 (4.1%) patients were transfused with platelets. 160 random donor platelets and 65 single donor platelets were transfused. Reaction rate was 3.11% and minimum reactions occurred when single donor platelets were used.


dengue virus, thrombocytopenia, platelet transfusion, random donor platelets, single donor platelets