Abstract

This prospective, observational study evaluated the efficacy of Biofilm at the palatal connective tissue graft donor site. Carried out at the Catholic University of Honduras, Patients selected according to rigorous criteria followed a treatment plan that included the application of Biofilm three times a day. Using clinical photographs; color, contour, and texture analyzes were performed, along with pain assessment using the visual analogue scale (VAS) on postoperative days 3, 7, 14, and 21. The results revealed a consistent improvement in connective tissue color across all age groups, supported by progressive decrease in VAS scores, indicating a significant reduction in postoperative pain. The analysis of contour changes highlighted the ability of the Biofilm to facilitate healing and maintain the structural integrity of the palate, while the analysis of texture changes showed a positive recovery in the surface appearance of the tissues. Together, these findings suggest that the application of Biofilm contributes not only to the aesthetic improvement of the connective tissue but also to the patient’s comfort during recovery. Although the study has limitations, such as the lack of a control group, it provides a valuable basis for future research in optimizing postoperative recovery in patients undergoing palatal connective tissue graft procedures. These preliminary results underscore the need for additional research with a more robust design to validate and extend these findings.

Keywords

unilaminar honey membrane, healing, palate graft, texture, color, pain