Abstract

Introduction: Chordomas are rare tumors derived from embryonic remnants of the notochord. They commonly affect the axial skeleton, including the skull base and sacral region, posing challenges in treatment due to their aggressive nature and high recurrence rates. Case presentation: Patient GKHP, a 43-year-old female, presented with a recurrent clivus chordoma following initial surgery in 2010. Endoscopic endonasal resection was performed in July 2022, resulting in a cerebrospinal fluid fistula postoperatively. Reconstruction utilized various materials, requiring a second surgical intervention and antibiotic treatment. Discussion and conclusion: Chordomas represent a small percentage of malignant bone tumors, originating from primitive notochord remnants. While surgical excision remains the primary treatment, challenges persist due to tumor location and invasiveness. Endoscopic techniques offer promise in managing complex cases, although proximity to vital structures presents ongoing challenges. A multidisciplinary approach, including surgery and radiotherapy, remains essential in achieving successful outcomes for patients with chordomas.

Keywords

chordoma, skull base, clivus, endoscopic surgery