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Candida auris: an emerging life-threatening fungal pathogen of global public health concern

Journal of Bacteriology & Mycology: Open Access
Mahendra Pal,1 Firaol Tariku,2 Dhwani Upadhyay,3 Claudete Rodrigues Paula,4 Bheemshetty Patil5


The multidrug-resistant yeast Candida auris has in recent times emerged to be known as an alarming threat to global health. Since it was first discovered in Japan in 2009, the virus has spread to more than 50 nations, resulting in significant epidemics in health care facilities throughout the world. It is currently endemic in several regions of Asia and Africa, where infection death rates have been estimated to reach up to 72% in some cases. Treatment for this infection is complicated by its resistance to numerous antifungal drugs, and its threat level is increased by its ability to elude normal laboratory identification techniques. Due to its ability to colonize skin and other surfaces, Candida auris is especially harmful in healthcare settings as it can spread throughout hospitals as well as between them. Its simultaneous emergence on multiple continents in genetically diverse clades highlights the complexity of its epidemiology and the difficulties in controlling it. Although the exact origins of this virus are still unknown, theories indicate that bird migration and global warming may have had a role in its spread. Making a diagnosis of Candida auris is still difficult. Because of its multidrug resistance and persistent transmission, Candida auris requires innovative therapeutic and preventive approaches for effective management. To combat Candida auris, this paper discusses its epidemiology, diagnostic methods, treatment choices, and preventative and control measures.


Candida auris, emerging pathogen, health care settings, multidrug-resistant, public health