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Inhibin alpha as a tumor marker for early detection of uterine tumors similar to ovarian sex cord tumors


Urology & Nephrology Open Access Journal
<font face="Arial, Verdana"><span style="font-size: 13.3333px;">Farkhondeh Pouresmaeili,<sup>1</sup> Shima Mohammadian,<sup>2</sup> Soheila Sarmadi,<sup>3 </sup>Aida Mohammadian<sup>4</sup></span></font>

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Abstract

Background: Uterine tumors resembling ovarian sex cord tumors (UTROSCT) are a rare type of endometrial sarcoma characterized by uterine stroma. These tumors mimic reproductive cord structures and typically exhibit benign behavior. A thorough evaluation of histological and immunohistochemical features is crucial for accurate diagnosis and effective management of these cases.
Case presentation: This report discusses a 45-year-old Iranian woman who presented with a large uterine mass and subsequently underwent a total hysterectomy and bilateral oophorectomy. Pathological analysis identified the lesion as a uterine sac. Notably, there was a significant difference in Inhibin A levels before and after surgery, suggesting that the tumor was responsible for the secretion of this factor.
Conclusion: We recommend that during the initial assessment of similar patients, the levels of this factor should be included in routine blood tests.

Keywords

Uterine tumors, malignancy, salpingo oophorectomy, case report

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