Abstract

Rosacea is a chronic inflammatory skin disease that has prevalence in women in theirs latest 30-60’s with low phototype, event thought it can happen in high phototypes. It is characterized by facial erythema, telangiectasia, papules, pustules and possible ocular manifestations; its etiology is unknown and possibly multifactorial were genetics, environmental, immune, microbial, neurovascular e triggering factors play a huge role in. This case report has the objective of presenting the benefits of the association of Polydeoxyribonucleotide (PDRN) and drug- delivery microneedling in the management of inflammation, vasodilation, and angiogenesis caused by rosacea. This study was based in a protocol using intense pulsed light (IPL), drug- delivery microneedling and PDRN was created based on the sensibility and inflammation of the patient skin at the beginning of treatment; IPL and drug- delivery microneedling were done monthly, in a two- week interval between the sessions. In total, four sessions of IPL and three sessions of drug-delivery microneedling were realized in a period of four months. This report brings results that corroborate the benefit of PDRN in the management of rosacea and skin kept in sensibility until 75%, when analyzed with Dermavision IA.

Keywords

PDRN, microneedling, rosacea, drug- delivery, intense pulsed light