Abstract

The SCA are a group of neurodegenerative disorders with autosomal dominant inheritance pattern, with symptoms caused by dysfunction of the cerebellum and brainstem, as well as their associated pathways and connections. These manifestations affect balance, gait, speech, as well as ocular conditions due to macular and retinal degeneration. Spinocerebellar Ataxia type 2 (SCA2) is the second among the spinocerebellar ataxias with the highest prevalence worldwide, and it is in Holguín Cuba, where it reaches its highest prevalence rate. A descriptive observational study will be carried out, with the objective of evaluating the biochemical values and nutritional status of patients with mild and moderate SCA2 in Holguin province in the year 2024. Analysis and synthesis to reveal the actuality of the problem that was investigated and to analyze the data and information related to it, historical- logical using for the analysis and determination of the antecedents and methodological theoretical foundation of leptospirosis, deduction - induction. The main variables studied were age, sex, BMI, biochemical and hematology analyses. The main results showed a decrease in BMI and an equal decrease in biochemical markers related to nutrition. The biochemical elements studied show a high relationship with the nutritional status of the patients. The high levels of glycemia and the low levels of cholesterol, triglycerides and albumin show a high correlation with the nutritional status of the patients.

Keywords

Ataxia type 2, SCA2, biochemical elements, nutrition