The Culture Score framework, developed under the PvtXAI initiative, introduces an innovative system to assess how cultural institutions contribute to raising awareness and preventing chronic diseases, including obesity, diabetes, and cardiovascular conditions. The framework conceptualizes cultural engagement as a performative act that influences health behaviors. It highlights arts and culture as critical, non-pharmacological interventions for health promotion, supported by evidence linking participation in artistic activities to improved mental well-being and reduced chronic disease risk. The Culture Score employs a multi-dimensional methodology, integrating social, economic, and environmental factors into a weighted scoring system that quantifies an institution’s potential for promoting health. Higher scores indicate strong alignment with chronic disease prevention, whereas lower scores identify opportunities for improvement. Recommendations derived from the framework parallel contemporary public health approaches, such as social prescribing, emphasizing structured cultural engagement as part of holistic health strategies. Ultimately, the Culture Score seeks to reposition cultural institutions as essential contributors to public health, promoting healthier communities through enhanced access to arts and culture.