Why are we failing to cure so many cases of invasive lobular breast cancer?
- Journal of Cancer Prevention & Current Research
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László Tabár, Peter B Dean, Li-Sheng Chen, Olga Puchkova, Amy Ming-Fang Yen,Hsiu-Hsi Chen, F Lee Tucker, Robert A Smith,Katalin Ormándi, Orsolya Oláh-Németh, Zoltán Veréb, András Vörös, Renáta Bozó
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Abstract
Review evidence for the site of origin of diffuse
invasive lobular carcinoma (ILC), supported by cell culture results. Describe
two distinct forms of classic ILC, which have vastly different long-term
outcomes. Recognition of the hybrid (stem) cell origin of classic ILC could
foster improvement of its currently inadequate management.
Keywords
breast cancer, invasive lobular carcinoma, imaging biomarkers, molecular biomarkers, long-term outcome.
