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Successful judgment-based steroid management of bevacizumab-induced acute kidney injury with suspected renal-limited thrombotic microangiopathy in a patient with colon cancer: a case report


Urology & Nephrology Open Access Journal
<font face="Arial, Verdana"><span style="font-size: 13.3333px;">Abdulrahman Bahatheq,<sup>1 </sup>Abdulaziz Mohammed Bajubair,<sup>1</sup> Abdullah Alaa Farid,<sup>1</sup> Rasha A.Alsulami,<sup>1</sup> Zahra Kadhem Abdulnabi,<sup>1 </sup>Ahmed AkL<sup>1,2,3</sup></span></font>

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Abstract

It is challenging to identify the aetiology of acute kidney injury in cancer patients since it can be multifactorial. Renal-limited thrombotic microangiopathy (rTMA) is a rare but recognized complication associated with certain antineoplastic therapies. Diagnosing rTMA in the context of bevacizumab therapy requires a high level of suspicion. In here, we report steroid responsive acute kidney injury associated with induction therapy with bevacizumab therapy.

Keywords

microangiopathy, bevacizumab therapy, kidney, angiogenesis

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