Abstract

Introduction: Delayed cord clamping (DCC) has demonstrated multiple neonatal benefits; however, its role in twin pregnancies remains controversial due to limited evidence and specific physiological considerations. Objective To explore neonatal outcomes associated with DCC in dichorionic twin pregnancies ≥34 weeks, using a comparative cohort of singleton newborns as a reference group. Methods: Retrospective comparative cohort study conducted in a tertiary care center. Dichorionic twins ≥34 weeks with immediate cord clamping (ICC) were compared with historical singleton controls managed with DCC. Descriptive and analytical statistics were performed, including relative risks (RR) with 95% confidence intervals (CI). Results: Thirty-two twin newborns (16 pairs) and corresponding controls were analyzed. Neonatal anemia was less frequent in the DCC group (25% vs 56.25%; RR 0.65, 95% CI 0.45–0.94). No mortality was observed. Other outcomes showed no statistically significant differences. Conclusions: DCC may be associated with a lower incidence of neonatal anemia. However, findings should be interpreted cautiously due to methodological limitations. Prospective studies are required.

Keywords

Neonatal anemia